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A Comprehensive Review on Phytochemistry and Pharmacological Effects of Stinging Nettle (Urtica dioica)

[ Vol. 3 , Issue. 3 ]

Author(s):

Mona Semalty, Lokesh Adhikari, Divya Semwal, Anita Chauhan, Akash Mishra, Rupali Kotiyal and Ajay Semalty*   Pages 156 - 167 ( 12 )

Abstract:


Background and Objective: Urtica dioica (stinging nettle), a member of the Urticaceae family, has been used in various traditional systems of medicines since ancient times especially for joint pain, arthritis and prostate problems. Its roots and leaves contain a wide variety of bioactive constituents like sterols, fatty acids, lectins terpenes, phenylpropanes, lignans and coumarins. The leaves and root extract shows various activities like hypoglycemic, anti-inflammatory, antiproliferative, antioxidant, hypolipemic, antirheumatic, anticarcinogenic and antiviral activity. It shows its effects through the inhibition of aromatase, 5 α-reductase, cell proliferation and Na+, K+-ATPase inhibition.

Conclusion: The article reviews the phytochemistry and phytopharmacology of the plant.

Keywords:

Alopecia, analgesic, anti-arthritic, antihypertensive, anti-inflammatory, 5 alpha reductase inhibitor, BPH, herbal remedy, nettle, urtica.

Affiliation:

Department of Pharmaceutical Sciences, H.N.B. Garhwal (Central) University Srinagar Garhwal- 246174, Uttarakhand, Department of Pharmaceutical Sciences, H.N.B. Garhwal (Central) University Srinagar Garhwal- 246174, Uttarakhand, Department of Pharmaceutical Sciences, H.N.B. Garhwal (Central) University Srinagar Garhwal- 246174, Uttarakhand, Department of Pharmaceutical Sciences, H.N.B. Garhwal (Central) University Srinagar Garhwal- 246174, Uttarakhand, Department of Pharmaceutical Sciences, H.N.B. Garhwal (Central) University Srinagar Garhwal- 246174, Uttarakhand, Department of Pharmaceutical Sciences, H.N.B. Garhwal (Central) University Srinagar Garhwal- 246174, Uttarakhand, Department of Pharmaceutical Sciences, H.N.B. Garhwal (Central) University Srinagar (Garhwal)-246174, Uttarakhand

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