Omar Husham Ahmed Al-Attraqchi, Pran Kishore Deb* and Noor Husham Ahmed Al-Attraqchi Pages 1 - 18 ( 18 )
The extracts of Valeriana officinalis are one among the most widely used herbal medications worldwide. The roots of this medicinal plant have been shown to be rich in several biologically active of phytochemicals. Various classes of chemical compounds are present in the roots of Valeriana officinalis including, terpenes, valepotriates and lignans. High amount of bioactive chemical components of this plant makes it potential for medicinal applications in different pathological conditions such as in sleep disorders, cardiovascular diseases, anxiety and depression. The most common medicinal use of Valeriana officinalis extract is the treatment of insomnia and improving the quality of sleep. The mild sedative effects of the extract as well as the absence of any significant side effects makes it a popular alternative to the synthetic sedative drugs which are usually associated with undesirable adverse effects. In this review, the bioactive chemical components of Valeriana officinalis and their pharmacological activities are discussed with special emphasis on their possible mechanisms of action and the medicinal applications.
Valeriana officinalis, valerian, valerenic acid, valepotriates
Faculty of Pharmacy, Philadelphia University, Amman, Faculty of Pharmacy, Philadelphia University, Amman, Depratment of Pharmacognosy, Mosul University, Mosul