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Naturally Available Nitrogen-Containing Fused Heterocyclics as Prospective Lead Molecules in Medicinal Chemistry

[ Vol. 7 , Issue. 1 ]

Author(s):

Nivedita Bhardwaj, Akashdeep Pathania and Pradeep Kumar*   Pages 5 - 27 ( 23 )

Abstract:


Heterocyclic compounds constitute one of the largest and most versatile families of organic compounds. There are many heterocyclic compounds that are being isolated from natural sources and day by day the number is increasing rapidly due to their enormous utility. Nitrogen containing heterocyclic compounds have a prominent role in medicinal chemistry, biochemistry and other streams of science. In this review, we have covered most of the biologically active nitrogen containing heterocyclic compounds obtained from the natural sources including indole, carbazole, quinoline, isoquinoline and benzothiazole ring system. These isolated nitrogen containing heterocyclic compounds render wide spectrum of biological activities including antifungal, anti-inflammatory, antibacterial, antioxidants, anticonvulsant, anti-allergic, herbicidal and anticancer activities.

Keywords:

Heterocyclic compounds, indole, carbazole, quinoline, isoquinoline, benzothiazole.

Affiliation:

Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda, Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda, Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda



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