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Nature-derived Quinolines and Isoquinolines: A Medicinal Chemistry Perspective

Author(s):

Mohit Gupta* and Saloni Patel   Pages 1 - 19 ( 19 )

Abstract:


Quinoline and isoquinoline motifs are commonly encountered in natural products of diverse origins. These moderately basic fused-heterocyclic rings containing natural products are adorned with remarkable biological activities with clinical use in various diseases demonstrating nature elegance and creativity. Therefore, these privileged rings have attracted profound interest from the scientific community. In this review, we have discussed medicinal chemistry perspective of the natural products containing quinoline and isoquinoline scaffolds.

Keywords:

Quinoline, isoquinoline, medicinal chemistry, natural products, fused-heterocycle

Affiliation:

Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, Pennsylvania 15282, Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, Pennsylvania 15282



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