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Genus Calotropis: A Hub of Medicinally Active Phytoconstituents

Author(s):

Shelly Pathania, Parveen Bansal, Prasoon Gupta and Ravindra Kumar Rawal*   Pages 1 - 20 ( 20 )

Abstract:


Traditional medicines derived from plants and other natural sources have several advantages over synthetic drugs when used in the management of pathological conditions. Natural product based therapies are devoid of adverse effects associated with synthetic drugs. C. procera and C. gigantea are the flowering herbal plants, belonging to the genus Calotropis family Apocynaceae, which, due to its diverse pharmacological profile, has been widely employed in Ayurveda, Unani, Siddha and other traditional systems for the treatment of various diseases all around the globe. The various part of the plant are rich in number of phytoconstituents such as cardiac glycosides, flavonoids, terpenoids, steroids, phenolic compounds, proteins etc. Due to the presence of multiple constituents, the plant possess diverse biological activities such as analgesic, antitumor, antihelmintic, antioxidant, hepatoprotective, antidiarrhoeal, anticonvulsant, antimicrobial, oestrogenic, antinociceptive, antimalarial activity etc. The present review provides comprehensive information about various phytochemical constituents of the plant along with their medicinal importance.

Keywords:

Calotropis procera, C. gigantea, phytoconstituents, cardenolides, flavanoids, terpenes, sterols

Affiliation:

Research Scholar, Department of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda (Punjab)151001, University Centre of Excellence in Research, Baba Farid University of Health Sciences, Faridkot, Punjab, Natural Product Chemistry Division, Indian Institute of Integrative Medicine, Canal Road, Jammu-180001, Department of Chemistry, Maharishi Markandeshwar (Deemed to be University), Mullana-133207, Ambala, Haryana



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